Expression of D-Type Cyclins in Normal and Neoplastic Rat Pituitary1
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چکیده
منابع مشابه
the role of type-d personality, social support and self-compassion in prediction of health behaviors in coronary heart disease patients
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15 صفحه اولPlant D-type cyclins and the control of G1 progression.
The basic pattern of controls that operate during the G1 phase of the plant cell cycle shows much closer similarity to animals than to the yeasts and other fungi. The activity of D-type cyclin (CycD) kinases is induced in response to stimulatory signals, and these phosphorylate the plant homologue of the retinoblastoma tumour susceptibility (Rb) protein. It is likely that Rb phosphorylation res...
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چکیده ندارد.
The D-type cyclins and their role in tumorigenesis.
The D-type cyclins are expressed during the progression from G0/G1 to S phase in the mammalian cell cycle. There is considerable evidence that they contribute to the development of specific cancers, both in humans and in mouse models. For example, cyclin D1 can be activated by chromosomal translocation, DNA amplification and retroviral integration. Cyclins D1, D2 and D3 preferentially associate...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 1998
ISSN: 0013-7227,1945-7170
DOI: 10.1210/endo.139.4.5955